Funded Studies

Orthopaedic Medicine Research Grants

Spring 1999
Gobinda Sarkar, PhD
Evaluation of hDhm2p Expression,
Human Homolog of a DNA
Recombination Gene, in
Musculoskeletal Tumors
Mayo Clinic

Fall 1999
Sheldon Lin, MD
Delayed Fracture Healing in Diabetes
Mellitus: Effect of Systemic Control
with Insulin and Local Insulin Delivery
UMDNJ-New Jersey Medical School

Christopher Harner, MD
Function of the PCL and Posterolateral
Structures in the Intact, Injured,
and Reconstructed Knee
University of Pittsburgh

Spring 2000
Jeffrey Weiss, PhD
Effective Anti-angiogenic Treatment
of Ligament Healing
University of Utah

Deborah Ciombor, PhD
Stimulation of Chondrogenic
Differentiation by Polymer-Encapsulated
Growth Factors
Rhode Island Hospital

Fall 2000
Michael Hudson, PhD (Deceased)
S.aureus-Infected Osteoblasts Initiate
an Inflammatory Response
UNC at Charlotte

Michael Hadjiargyrou, PhD
Molecular Characterization of
Two Novel Genes Differentially
Expressed During Fracture Healing
SUNY at Stony Brook

Richard Debski, PhD
Analysis of Reconstruction
Procedures for Acromioclavicular
Joint Injury
University of Pittsburgh
Brian Davis, PhD
Mechanisms Underlying Calcaneal
Fractures
Cleveland Clinic Foundation

Gerald Williams, MD
Tendon to Bone Healing: Role of
the Mechanical Environment
University of Pennsylvania

Spring 2001
Claudia Kappen, Dr.rer.nat.
Functional Genomics of Cartilage
Development
University of Nebraska Medical Center

Karen Yates, PhD
Function of Wnt Genes in Chondroblast
Differentiation in vitro
Brigham & Women’s Hospital

Sean Scully, MD, PhD
The Role of Tenascin in
Chondrosarcoma Metastases
Mayo Clinic

Fall 2001
Gobinda Sarkar, PhD
Evaluation of a Human DNA
Recombination Gene, hDhm2,
in Musculoskeletal Tumors
Mayo Clinic

Evan Flatow, MD
Assessment of Damage Accumulation
in Rat Tendons
Mt. Sinai School of Medicine

Long-En Chen, MD, PhD
Nitric Oxide in Reperfused
Peripheral Nerve
Duke University Medical Center

Spring 2002
Maury L. Hull, PhD
Increases in Anterior Laxity and
Graft Slippage During Aggressive
Rehabilitation of Knees Reconstructed
with Bone-Patellar Tendon-Bone and
Hamstring Anterior Cruciate Ligament
Grafts
University of California, Davis

Scott A. Rodeo, MD
Meniscal Allograft Transplantation in the
Sheep Knee: Evaluation of Early Markers
for Degenerative Change and Assessment
of Surgical Timing on Articular Cartilage
Deterioration
Hospital for Special Surgery

Zong-Ming Li, PhD
Biomechanical Evaluation of
Hand Motor Function
University of Pittsburgh

Fall 2002
Tong-Chuan He, MD, PhD
Expression Profiling Analysis of
BMP9-mediated Osteoblastic
Differentiation
University of Chicago

Michael J. Zuscik, PhD
Cell and Molecular Effects of Nicotine
on Chondrogenesis and Cartilage
Differentiation
University of Rochester

Spring 2003
Ranjan Gupta, MD
Schwann Cell Response to the
Biomechanical Forces Associated
with Carpal Tunnel Syndrome
University of California, Irvine

Fall 2003
Wen-Ning Qi, MD
NF-(B Signaling Pathway Regulates
iNOS Expression in Response to
Reperfusion Injury
Duke University Medical Center

Bang H. Hoang, MD
The Role of Wnt Signaling in the
Progression of Osteosarcoma
University of California, Irvine

Spring 2004
John M. Cavanaugh, MD
An Experimental Study of Mechanical,
Neurophysiological and Structural
Changes of Spinal Nerve Roots Caused
By Tensile Loading
Wayne State University

Matthew B. Dobbs, MD
A Genome-Wide Linkage Analysis
for Idiopathic Clubfoot
Washington University School
of Medicine

Fall 2004
Francis Y. Lee, MD
Targeting Cell Survival Pathways
In Chondrosarcoma
Columbia University

Joseph B. Myers, PhD, ATC
Identifying Contributors to Functional
Impairment in Patients with Rotator
Cuff Tears
University of Pittsburgh

Darryl G. Thelen, PhD
Hamstring Muscle Mechanics and
Function During Sprinting
The University of Wisconsin-Madison

Kristy Weber, MD
The Role of IL-6 in the Growth of Renal
Cell Carcinoma Bone Metastasis
Johns Hopkins University

Spring 2005
Darryl D. D’Lima, MD
Cytoprotection in the Treatment of Cartilage
Lesions
Scripps Clinic

Xiaojuan Li, PhD
Assessment of Cartilage and Subchondral
Bone Injuries of the Knee Following Anterior
Cruciate Ligament Tear with High Field
Magnetic Resonance Imaging
University of California, San Francisco

Fall 2005
Javad Parvizi, MD, FRCS
Molecular Mechanism of Arthrofibrosis Following
Total Knee Arthroplasty
Rothman Institute at Thomas Jefferson University

Qiuqian Wu, MD, PhD
Age-Related Changes in TGF-B/BMP Signaling
Impair Fracture Healing in a Mouse Model
University of Rochester

Spring 2006
Esmaiel Jabbari, PhD
Synergistic Effects of Microencapsulated BMP and
RGD Peptide on Osteoinductivity of Injectable In-Situ
Crosslinkable Poly(lactide) Scaffolds
University of South Carolina

Amy J. Wagoner Johnson, PhD
Evolution of Bone Formation and the Effects on
Mechanical Deformation and Damage Mechanisms
in Tailorable Scaffolds
University of Illinois – Urbana-Champaign

Fall 2006
Robert L. Mauck, PhD
Meniscus Tissue Engineering with Anisotropic
Biodegradable Nanofibrous Scaffolds
University of Pennsylvania

Fall 2007
Johnna Temenoff, PhD
Co-Culture Constructs to Promote Regeneration
of the Ligament-Bone Interface
Georgia Institute of Technology

Lei Wei, MD, PhD
Disruption of SDF-1 Signaling Inhibits Cartilage
Degeneration and Attenuates Osteoarthritis Pathogenesis
Brown Medical School

Fall 2008
Hani A. Awad, MD
PTH Treatment for Enhanced Massive Bone
Allograft Union
University of Rochester

Hans-Christoph Pape, MD
Damage Control Orthopaedics: The Effects on
Local and Systemic Complications
University of Pittsburgh

PRIOR TO 2015

The Foundation had funded 38 Grant Applications in the total amount of $3,796,296.

Upon receiving a large charitable contribution to the Foundation, the Foundation, as reconstituted, has again begun funding, primarily through collaboration
efforts with OREF and AOSSM.

FUTURE COLLABORATION COMMITMENTS

2017 OREF – $50,000
Resident Research Grants

2017 OREF – $50,000
James R. Andrews
Collaborative Research Agenda in the Prevention of Youth Sports Injuries

2017 OREF – $25,000
Russell Warren
Sports Grant Program

2017 AOSSM – $50,000
TO BE NAMED. FOUNDATION GRANT

2018 OREF – $50,000
James R. Andrews
Collaborative Research Agenda in the Prevention of Youth Sports Injuries

2018 OREF – $25,000
Russell Warren
Sports Grant Program

2018 AOSSM – $50,000
TO BE NAMED. FOUNDATION GRANT

2019 AOSSM – $50,000
TO BE NAMED. FOUNDATION GRANT

TOTAL FOUNDATION GRANTS-COMMITMENTS 2015-2019: $520,000

The Foundation has funded, or committed to fund, the following studies and programs:

2015 OREF
Daniel Mark Koehler
U. of Iowa Hosp./clinic
Time Driven Activity Based Cost Analysis of Open vs Endo Carpal Tunnel Release

2015 OREF
Manish Suresh Noticewala
Columbia U. Med
Pain, Function and Performance Assessment in Overhead Youth Athlete

2015 OREF
Bawa, Harpreet, Singh
U. of Chicago
Growth Factor Expression During Tendon Healing in 3 Tendon Types

2015 OREF
Mark Joseph Gage
NYU Hospital-Joint Disease
Which Surgical Treatment Method of Femoral Neck Fractures Allows for More Rapid Return to Function

2015 OREF
Brent Gregory Witten
WVU Research Corp
Outpatient Compliance with Portable Pneumatic Compression Device

2015 OREF
Amit Jain
John Hopkins Med School
Duration of Antibiotic Prophylaxis in Orthopaedic Trauma

2016 OREF
Steven DiSegna
U. Mass
Predicting Early Failure in Total Knee Arthoplasty

2016 OREF
Chris Dobson
UC- San Diego
Biomarkers of Neutrophil Extracellular Trap Formaiton and Relationship to Adipoisity in Total Joint Arthoplasty

2016 OREF
Matthew Grosso
Columbia
Adductor Canal Block Versus Periartiular Bupivacaine Injection in TKA

2016 OREF
Jason Ho
Cleveland Clinic
Long Term Effects of Glenoid Component Version in Total Shoulder Artho.

2016 OREF
Austin Pitcher
UC-San Francisco
Biomechanical Evaluation of Augmentation Strategies For Fixation of Proximal Humerous Fractures in Osteoporotic Bone

2016 OREF
Brett Rosenthal
Northwestern U.
Development of 3D- printed Hyperelastic Bone compositions for Bone Regeneration and Spine Fusion

2016 OREF
Bryan Smith
Loyola, Chicago
Development of a Real Time Model of Foot and Ankle Kinematics During Simulated Gait-Pilot Study

2016 OREF
J. Tangtiphalboontana
UC-San Francisco
Effect of Ibuprofen on Postoperative Narcotic Consumption and Shoulder Functional Outcomes After Arthoscopic Rotator Cuff Repair

2016 OREF
Arvind Von Keudell
Beth Israel Deaconess
Biomechanical Properties of Intramedullary Suture Anchor vs Traditional tension band Wiring in Osteoporotic Olecranon Fractures

2016 OREF
Kent Yamaguchi
UC-Los Angeles
The Effect of Proximal Tibia Anterior Closing Wedge Osteotomy on ACL Forces and Knee Kinematics

2016 OREF – $50,000
James R. Andrews
Collaborative Research Agenda in the Prevention of Youth Sports Injuries

2016 OREF – $25,000
Russell Warren
Sports Grant Program

2016 OREF – $15,000
Poster
Program-AOSSM Annual Meeting